Chloride → Ethyl 3-(dimethylamino)-2-(5-(6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-yl)-2-fluorobenzoyl)acrylate
Reaction equation
[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:22]2[s:23][cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[n:26]2)[c:9](-[c:12]2[cH:13][cH:14][c:15]([F:21])[c:16]([C:17](=[O:18])[OH:19])[cH:20]2)[cH:10][n:11]1)=[O:31].[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:36][N:37]([CH:38]=[CH:39][C:40](=[O:41])[O:42][CH2:43][CH3:44])[CH3:45].[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[CH3:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1.[Cl-:53].[O-:54][C:55]([CH:56]=[CH2:57])=[O:58].[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[OH2:71].[S:32]([Cl:33])([Cl:34])=[O:35]>>[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:22]2[s:23][cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[n:26]2)[c:9](-[c:12]2[cH:13][cH:14][c:15]([F:21])[c:16]([C:17](=[O:18])[C:39](=[CH:38][N:37]([CH3:36])[CH3:45])[C:40](=[O:41])[O:42][CH2:43][CH3:44])[cH:20]2)[cH:10][n:11]1)=[O:31]Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-f8a185907a904f98a9b0112f00ad9de2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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