Ammonium → Tert-butyl 3-(3-chloro-5-fluorophenyl)-3-hydroxyazetidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:9])[cH:5][c:6]([F:8])[cH:7]1.[C:12](=[O:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[N:19]1[CH2:20][C:21](=[O:23])[CH2:22]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[Cl-:24].[I:11].[Mg:10].[NH4+:25].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[OH2:36]>>[c:2]1([C:21]2([OH:23])[CH2:20][N:19]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:22]2)[cH:3][c:4]([Cl:9])[cH:5][c:6]([F:8])[cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-eb292f9feecd4bc6b9ae7590c50cdc26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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