1,2-Dichloroethane → 3-(3,3-dimethylbutyl)-2-[3-fluoro-2-(2-piperidin-1-ylethylamino)phenyl]-5-[2-oxo-2-[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one
Reaction equation
[CH2:49]([Cl:50])[CH2:51][Cl:52].[CH3:77][CH2:78][O:79][C:80]([CH3:81])=[O:82].[CH:63]([N:64]([CH2:65][CH3:66])[CH:67]([CH3:68])[CH3:69])([CH3:70])[CH3:71].[N:1]1([CH2:7][CH2:8][NH:9][c:10]2[c:11]([CH:17]3[S:18][CH:19]([CH2:29][C:30](=[O:31])[OH:32])[C:20](=[O:28])[N:21]3[CH2:22][CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[cH:12][cH:13][cH:14][c:15]2[F:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH:33]1[CH2:34][CH2:35][CH:36]([n:39]2[c:40](=[O:48])[nH:41][c:42]3[n:43][cH:44][cH:45][cH:46][c:47]23)[CH2:37][CH2:38]1.[O:72]=[CH:73][N:74]([CH3:75])[CH3:76].[OH2:83].[OH:53][n:54]1[c:55]2[c:56]([cH:57][cH:58][cH:59][cH:60]2)[n:61][n:62]1>>[N:1]1([CH2:7][CH2:8][NH:9][c:10]2[c:11]([CH:17]3[S:18][CH:19]([CH2:29][C:30](=[O:32])[N:33]4[CH2:34][CH2:35][CH:36]([n:39]5[c:40](=[O:48])[nH:41][c:42]6[n:43][cH:44][cH:45][cH:46][c:47]56)[CH2:37][CH2:38]4)[C:20](=[O:28])[N:21]3[CH2:22][CH2:23][C:24]([CH3:25])([CH3:26])[CH3:27])[cH:12][cH:13][cH:14][c:15]2[F:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-33ad3bb2aa294cc295836d60c3cc748a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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