Tetrahydrofuran → Tert-butyl 3-[1-(3-chlorophenyl)-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate
Reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([C:23]([c:24]2[cH:25][c:26]([Cl:30])[cH:27][cH:28][cH:29]2)=[O:31])[CH2:20][CH2:21][CH2:22]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[Cl:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9].[I:2].[Mg:1]>>[CH2:4]([CH2:5][CH2:6][CH2:7][O:8][CH3:9])[C:23]([CH:19]1[CH2:18][N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21][CH2:20]1)([c:24]1[cH:25][c:26]([Cl:30])[cH:27][cH:28][cH:29]1)[OH:31]Participants
6
Sources & evidence
- ORD record
- ord-e7dbc69f097b47c19859b26d4f91b667
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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