Dimethylformamide → HCID 58982139, compound

HRID 1182513Notes

Reaction equation

HRID 1182513 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.CI.[CH3:15][N:16]([CH:18]=[O:19])C>C1COCC1>[CH:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[CH:12][C:3]=1[CH2:2][N:16]1[CH2:15][CH2:5][CH2:4][CH2:3][CH2:2][C:18]1=[O:19]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 6328Methyl iodideHCID 703202-Bromomethylnaphthalene

Product 1

HCID 58982139HCID 58982139, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following the procedure described in Example 122, step 1, but substituting respectively 2-bromomethylnaphthalene for methyl iodide, and DMF for THF, the title compound 217 was obtained in 97% yield. MS (ESI)=254 (MH+).

Sources & evidence

ORD record
ord-c7ac6b1be47e45fe9c6aedf018ae421e
Source dataset
uspto-grants-2007_10
Patent number
US07288567B2

Reaction notes

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