Hydrochloric Acid → 2-(4-Chloro-phenyl)-1-[1-cyclohexyl-2-(pyridin-3-yloxy)-ethyl]-5,6-difluoro-1H-benzoimidazole
Reaction equation
[Br:10][CH2:11][CH:12]([CH:13]1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1)[n:19]1[c:20](-[c:30]2[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]2)[n:21][c:22]2[c:23]1[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]2.[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[ClH:37].[H-:8].[Na+:9].[OH:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)[CH2:11][CH:12]([CH:13]1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1)[n:19]1[c:20](-[c:30]2[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]2)[n:21][c:22]2[c:23]1[cH:24][c:25]([F:29])[c:26]([F:28])[cH:27]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-530f5e8c63ea4466ba0b1cef13ff6606
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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