1,2-Dimethoxyethane → 2-methyl-4-(3-pyridinyl)-3-butyn-2-ol

HRID 1209059Notes

Reaction equation

HRID 1209059 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[CH3:15][C:16]([CH3:17])([C:18]#[CH:19])[OH:20].[CH3:21][CH2:22][O:23][C:24](=[O:25])[CH3:26].[CH3:27][O:28][CH2:29][CH2:30][O:31][CH3:32].[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cu:33][I:34]>>[c:2]1([C:19]#[C:18][C:16]([CH3:15])([CH3:17])[OH:20])[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 80711,2-DimethoxyethaneHCID 82582-Methyl-3-butyn-2-olHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 122863-BromopyridineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

Product 1

HCID 27840362-methyl-4-(3-pyridinyl)-3-butyn-2-ol

Sources & evidence

ORD record
ord-e14a258c1f984ee69e6699026a6bf851
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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