Ammonium → 5-(6-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylsulfanyl)-thiophen-2-ylamine

HRID 1214911Notes

Reaction equation

HRID 1214911 reaction equation
[CH3:3][N:4]([CH3:5])[CH:6]=[O:7].[CH3:8][CH2:9][OH:10].[Cl-:1].[Fe:35].[N+:11]([O-:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([S:19][c:20]2[c:21]3[c:22]([n:23][cH:24][n:25]2)[nH:26][c:27](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:28]3)[s:18]1.[NH4+:2].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH2:41]>>[NH2:11][c:14]1[cH:15][cH:16][c:17]([S:19][c:20]2[c:21]3[c:22]([n:23][cH:24][n:25]2)[nH:26][c:27](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:28]3)[s:18]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 962WaterHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 23925IronHCID 589312964-(5-Nitro-2-thiophenylsulfanyl)-6-phenyl-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 589310535-(6-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylsulfanyl)-thiophen-2-ylamine

Sources & evidence

ORD record
ord-e599e84f095d41ba937e21e95492de57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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