Dimethylformamide → 3-(1-cyanocyclopropyl)-N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}thio)phenyl]benzamide
Reaction equation
[C:24](#[N:25])[C:26]1([c:29]2[cH:30][c:31]([C:32](=[O:33])[OH:34])[cH:35][cH:36][cH:37]2)[CH2:27][CH2:28]1.[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[CH3:49][N:50]([CH3:51])[C:52](=[O:53])[CH3:54].[Cl:38][C:39]([C:40]([Cl:41])=[O:42])=[O:43].[NH2:1][c:2]1[cH:3][c:4]([S:8][c:9]2[cH:10][cH:11][c:12]3[n:13]([n:14]2)[cH:15][c:16]([NH:18][C:19](=[O:20])[CH:21]2[CH2:22][CH2:23]2)[n:17]3)[cH:5][cH:6][cH:7]1.[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1>>[NH:1]([c:2]1[cH:3][c:4]([S:8][c:9]2[cH:10][cH:11][c:12]3[n:13]([n:14]2)[cH:15][c:16]([NH:18][C:19](=[O:20])[CH:21]2[CH2:22][CH2:23]2)[n:17]3)[cH:5][cH:6][cH:7]1)[C:32]([c:31]1[cH:30][c:29]([C:26]2([C:24]#[N:25])[CH2:27][CH2:28]2)[cH:37][cH:36][cH:35]1)=[O:33]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fd75c31c784a48699db97f2413d55f5f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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