1,2-Dichloroethane → 4-Bromo-1-cyclopropylpyridin-2(1H)-one

HRID 1217239Notes

Reaction equation

HRID 1217239 reaction equation
[Br:1][c:2]1[cH:3][c:4](=[O:8])[nH:5][cH:6][cH:7]1.[C:27](=[O:28])([O-:29])[O-:30].[CH:9]1([B:12]([OH:13])[OH:14])[CH2:10][CH2:11]1.[Cl-:33].[Cl:35][CH2:36][CH2:37][Cl:38].[NH4+:34].[Na+:31].[Na+:32].[n:15]1[cH:16][cH:17][cH:18][cH:19][c:20]1-[c:21]1[cH:22][cH:23][cH:24][cH:25][n:26]1>>[Br:1][c:2]1[cH:3][c:4](=[O:8])[n:5]([CH:9]2[CH2:10][CH2:11]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ion2×HCID 14742,2'-BipyridineHCID 19660Carbonate IonHCID 8171154-Bromo-2-hydroxypyridineHCID 2760897Cyclopropylboronic acid

Product 1

HCID 596356474-Bromo-1-cyclopropylpyridin-2(1H)-one

Sources & evidence

ORD record
ord-0a6ad2174a7a4985b1a099b9ff4f1e97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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