1,2-Dichloroethane → 3-[4-(4-Fluorobenzyl)-3-oxopiperazin-1-yl]-3-oxopropanenitrile
Reaction equation
[C:16](#[N:17])[CH2:18][C:19](=[O:20])[OH:21].[CH2:22]([Cl:23])[CH2:24][Cl:25].[CH:41]([N:42]([CH2:43][CH3:44])[CH:45]([CH3:46])[CH3:47])([CH3:48])[CH3:49].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:13])[CH2:9][NH:10][CH2:11][CH2:12]2)[cH:14][cH:15]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH:26][n:27]1[c:28]2[c:29]([cH:30][cH:31][cH:32][cH:33]2)[n:34][n:35]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:13])[CH2:9][N:10]([C:19]([CH2:18][C:16]#[N:17])=[O:20])[CH2:11][CH2:12]2)[cH:14][cH:15]1Participants
7
Sources & evidence
- ORD record
- ord-f12d1c8919eb415693cda624c9947835
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…