Bromide ion → 1-(Methoxycarbonyl)-2-(3-(trifluoromethyl)benzyl)piperidine-4-carboxylic acid
Reaction equation
[Br-:26].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:36][C:37]#[N:38].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[ClH:35].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([C:17](=[O:18])[O:19][CH3:20])[CH2:9][CH2:10][CH:11]([C:13](=[O:14])[O:15][CH3:16])[CH2:12]2)[cH:21][cH:22][cH:23]1)([F:24])[F:25].[Li+:27].[OH2:39]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([C:17](=[O:18])[O:19][CH3:20])[CH2:9][CH2:10][CH:11]([C:13](=[O:14])[OH:15])[CH2:12]2)[cH:21][cH:22][cH:23]1)([F:24])[F:25]Participants
9
Sources & evidence
- ORD record
- ord-9604fba1c6dc44148ca761ecb33a0952
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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