Acetate → Ethyl 3-[2-(2-(t-butoxycarbonylamino)ethoxy)-4-cyanophenyl]acrylate

HRID 1218059Notes

Reaction equation

HRID 1218059 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][O:11][c:12]1[cH:13][c:14]([C:15]#[N:16])[cH:17][cH:18][c:19]1[I:20].[C:21]([CH:22]=[CH2:23])(=[O:24])[O:25][CH2:26][CH3:27].[C:46]([O-:47])(=[O:48])[CH3:49].[C:51]([O-:52])(=[O:53])[CH3:54].[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45].[Pd+2:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][O:11][c:12]1[cH:13][c:14]([C:15]#[N:16])[cH:17][cH:18][c:19]1[CH:23]=[CH:22][C:21](=[O:24])[O:25][CH2:26][CH3:27]

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8821Ethyl AcrylateHCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 11111864t-Butyl [2-(5-cyano-2-iodophenoxy)ethyl]carbamate

Product 1

HCID 69921285Ethyl 3-[2-(2-(t-butoxycarbonylamino)ethoxy)-4-cyanophenyl]acrylate

Sources & evidence

ORD record
ord-c79f50fb7c2b45c99545ae1702ff4fbe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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