Ammonium → 1-[(2,4-difluorophenyl)methyl]-N-hydroxy-3-(2-methoxyethoxymethyl)pyrrolo[2,3-c]pyridine-5-carboxamide

HRID 121937Notes

Reaction equation

HRID 121937 reaction equation
[CH3:32][O-:33].[CH3:37][OH:38].[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[Cl-:35].[Cl:45][CH2:46][Cl:47].[ClH:29].[F:1][c:2]1[c:3]([CH2:4][n:5]2[cH:6][c:7]([CH2:18][O:19][CH2:20][CH2:21][O:22][CH3:23])[c:8]3[c:9]2[cH:10][n:11][c:12]([C:14]([O:16][CH3:15])=[O:17])[cH:13]3)[cH:24][cH:25][c:26]([F:28])[cH:27]1.[NH2:30][OH:31].[NH4+:36].[Na+:34]>>[F:1][c:2]1[c:3]([CH2:4][n:5]2[cH:6][c:7]([CH2:18][O:19][CH2:20][CH2:21][O:22][CH3:23])[c:8]3[c:9]2[cH:10][n:11][c:12]([C:14](=[O:16])[NH:30][OH:31])[cH:13]3)[cH:24][cH:25][c:26]([F:28])[cH:27]1

Participants

11

Reactant 10

HCID 223AmmoniumHCID 312ChlorideHCID 313Hydrochloric AcidHCID 787HydroxylamineHCID 887MethanolHCID 923Sodium ionHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 3826051MethoxideHCID 598558301h-Pyrrolo[2,3-c]pyridine-5-carboxylic acid,1-[(2,4-difluorophenyl)methyl]-3-[(2-methoxyethoxy)methyl]-,methyl ester

Product 1

HCID 115892181-[(2,4-difluorophenyl)methyl]-N-hydroxy-3-(2-methoxyethoxymethyl)pyrrolo[2,3-c]pyridine-5-carboxamide

Sources & evidence

ORD record
ord-2fed7ad598eb410c876d40382fd0b616
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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