1,2-Dichloroethane → 7-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butoxy}-6-fluoro-3,4-dihydro-1H-[1,8]naphthyridin-2-one
Reaction equation
[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:2][c:3]1[c:4]([N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:5][cH:6][cH:7][c:8]1[Cl:9].[Cl:47][CH:48]([Cl:49])[CH3:50].[Cl:51][CH2:52][CH2:53][Cl:54].[ClH:1].[F:23][c:24]1[c:25]([O:35][CH2:36][CH2:37][CH2:38][CH:39]=[O:40])[n:26][c:27]2[c:32]([cH:33]1)[CH2:31][CH2:30][C:29](=[O:34])[NH:28]2>>[Cl:2][c:3]1[c:4]([N:10]2[CH2:11][CH2:12][N:13]([CH2:39][CH2:38][CH2:37][CH2:36][O:35][c:25]3[c:24]([F:23])[cH:33][c:32]4[c:27]([n:26]3)[NH:28][C:29](=[O:34])[CH2:30][CH2:31]4)[CH2:14][CH2:15]2)[cH:5][cH:6][cH:7][c:8]1[Cl:9]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d66b3bc50b004514ab2881a32e2a3d49
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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