Hydrochloric Acid → 1-((3-Bromofuran-2-yl)methyl)-4-methylpiperazine

HRID 1220192Notes

Reaction equation

HRID 1220192 reaction equation
[Br:1][c:2]1[c:3]([CH:7]=[O:8])[o:4][cH:5][cH:6]1.[C:25]([O:26][BH-:27]([O:28][C:29](=[O:30])[CH3:31])[O:32][C:33](=[O:34])[CH3:35])(=[O:36])[CH3:37].[CH3:11][N:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1.[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:42][CH2:43][O:44][C:45]([CH3:46])=[O:47].[Cl:39][CH2:40][Cl:41].[ClH:10].[ClH:9].[Na+:38]>>[Br:1][c:2]1[c:3]([CH2:7][N:15]2[CH2:14][CH2:13][N:12]([CH3:11])[CH2:17][CH2:16]2)[o:4][cH:5][cH:6]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 923Sodium ionHCID 6344DichloromethaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 531671-MethylpiperazineHCID 2724942TriacetoxyborohydrideHCID 33672713-Bromo-2-furaldehyde

Product 1

HCID 710660911-((3-Bromofuran-2-yl)methyl)-4-methylpiperazine

Sources & evidence

ORD record
ord-dd6d52b7ae4e442eb87822551b33e304
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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