Water → N-{4-[(3-Chlorophenyl)amino]-3-cyano-6-quinolinyl]-2-butynamide
Reaction equation
[C:1]([C:2]#[C:3][CH3:4])(=[O:5])[OH:6].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:7][N:8]1[CH2:9][CH2:10][O:11][CH2:12][CH2:13]1.[Cl:14][C:15]([O:16][CH2:17][CH:18]([CH3:19])[CH3:20])=[O:21].[NH2:22][c:23]1[cH:24][c:25]2[c:26]([NH:35][c:36]3[cH:37][c:38]([Cl:42])[cH:39][cH:40][cH:41]3)[c:27]([C:33]#[N:34])[cH:28][n:29][c:30]2[cH:31][cH:32]1.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[OH2:53]>>[C:1]([C:2]#[C:3][CH3:4])(=[O:6])[NH:22][c:23]1[cH:24][c:25]2[c:26]([NH:35][c:36]3[cH:37][c:38]([Cl:42])[cH:39][cH:40][cH:41]3)[c:27]([C:33]#[N:34])[cH:28][n:29][c:30]2[cH:31][cH:32]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b568eedaffff42c69651754da814930c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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