Ammonium → 1-Benzyl-4-(4-fluoro-benzyl)-piperidin-4-ol
Reaction equation
[Br:2][CH2:3][CH2:4][Br:5].[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[N:22]1[CH2:23][CH2:24][C:25](=[O:28])[CH2:26][CH2:27]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cl-:29].[Cl:6][CH2:7][c:8]1[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]1.[Mg:1].[NH4+:30].[OH2:36]>>[CH2:7]([c:8]1[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]1)[C:25]1([OH:28])[CH2:24][CH2:23][N:22]([CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:27][CH2:26]1Participants
9
Sources & evidence
- ORD record
- ord-c461e04f485b4e20b860e40b63986d9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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