Hydrochloric Acid → 3-methyl-N-[3-({2-[(morpholin-4-ylacetyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)phenyl]pyridine-2-carboxamide

HRID 1227045Notes

Reaction equation

HRID 1227045 reaction equation
[C:69](=[O:70])([O-:71])[OH:72].[CH3:39][N:40]([CH3:41])[CH2:42][CH2:43][CH2:44][N:45]=[C:46]=[N:47][CH2:48][CH3:49].[CH3:74][N:75]([CH3:76])[C:77](=[O:78])[CH3:79].[CH:60]([N:61]([CH2:62][CH3:63])[CH:64]([CH3:65])[CH3:66])([CH3:67])[CH3:68].[ClH:38].[NH2:1][c:2]1[n:3][c:4]2[n:5]([cH:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18](=[O:19])[c:20]4[n:21][cH:22][cH:23][cH:24][c:25]4[CH3:26])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:27]1.[Na+:73].[O:28]1[CH2:29][CH2:30][N:31]([CH2:34][C:35](=[O:36])[OH:37])[CH2:32][CH2:33]1.[n:50]1([OH:51])[c:52]2[cH:53][cH:54][cH:55][cH:56][c:57]2[n:58][n:59]1>>[NH:1]([c:2]1[n:3][c:4]2[n:5]([cH:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18](=[O:19])[c:20]4[n:21][cH:22][cH:23][cH:24][c:25]4[CH3:26])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:27]1)[C:35]([CH2:34][N:31]1[CH2:30][CH2:29][O:28][CH2:33][CH2:32]1)=[O:36]

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 31374DimethylacetamideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 4389684-Morpholineacetic acidHCID 57749390N-{3-[(2-aminoimidazo[1,2-a]pyridin-6-yl)oxy]phenyl}-3-methylpyridine-2-carboxamide

Product 1

HCID 577493753-methyl-N-[3-({2-[(morpholin-4-ylacetyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)phenyl]pyridine-2-carboxamide

Sources & evidence

ORD record
ord-dcf19f813fbf4ab987834c8747b52350
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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