Hydrochloric Acid → N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-2-(phenylamino)nicotinamide
Reaction equation
[CH3:45][Si:46]([N-:47][Si:48]([CH3:49])([CH3:50])[CH3:51])([CH3:52])[CH3:53].[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60].[ClH:44].[F:13][c:14]1[c:15]([C:16](=[O:17])[NH:18][c:19]2[cH:20][cH:21][c:22]([O:25][c:26]3[n:27][cH:28][cH:29][cH:30][c:31]3-[c:32]3[n:33][c:34]([NH:38][CH3:39])[n:35][cH:36][cH:37]3)[cH:23][cH:24]2)[cH:40][cH:41][cH:42][n:43]1.[Li+:54].[NH2:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[O:8]1[CH2:9][CH2:10][CH2:11][CH2:12]1.[OH2:61].[OH2:62]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:14]1[c:15]([C:16](=[O:17])[NH:18][c:19]2[cH:20][cH:21][c:22]([O:25][c:26]3[n:27][cH:28][cH:29][cH:30][c:31]3-[c:32]3[n:33][c:34]([NH:38][CH3:39])[n:35][cH:36][cH:37]3)[cH:23][cH:24]2)[cH:40][cH:41][cH:42][n:43]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-a1f23f9cf677411bb09410057694a543
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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