Hydrochloric Acid → N-(4-tert-butyl-6-morpholin-4-ylmethyl-pyridin-2-yl)-2-[2-fluoro-4-(7-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-acetamide

HRID 1234836Notes

Reaction equation

HRID 1234836 reaction equation
[C:29]([CH3:30])([CH3:31])([CH3:32])[c:33]1[cH:34][c:35]([NH2:46])[n:36][c:37]([CH2:39][N:40]2[CH2:41][CH2:42][O:43][CH2:44][CH2:45]2)[cH:38]1.[CH3:85][CH2:86][O:87][C:88](=[O:89])[CH3:90].[CH:47]([N:48]([CH:49]([CH3:50])[CH3:51])[CH2:52][CH3:53])([CH3:54])[CH3:55].[ClH:1].[ClH:2].[F:3][c:4]1[c:5]([CH2:25][C:26](=[O:27])[OH:28])[cH:6][cH:7][c:8](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][n:22][cH:23][cH:24]2)[cH:18]3)[cH:9]1.[O:80]=[CH:81][N:82]([CH3:83])[CH3:84].[P-:56]([F:57])([F:58])([F:59])([F:60])([F:61])[F:62].[n:63]1([O:64][C:65]([N:66]([CH3:67])[CH3:68])=[N+:69]([CH3:70])[CH3:71])[c:72]2[n:73][cH:74][cH:75][cH:76][c:77]2[n:78][n:79]1>>[F:3][c:4]1[c:5]([CH2:25][C:26](=[O:27])[NH:46][c:35]2[cH:34][c:33]([C:29]([CH3:30])([CH3:31])[CH3:32])[cH:38][c:37]([CH2:39][N:40]3[CH2:41][CH2:42][O:43][CH2:44][CH2:45]3)[n:36]2)[cH:6][cH:7][c:8](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17](-[c:19]2[cH:20][cH:21][n:22][cH:23][cH:24]2)[cH:18]3)[cH:9]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 685432612-[2-Fluoro-4-(7-pyridin-4-ylimidazo[1,2-a]pyridin-3-yl)phenyl]acetic acidHCID 685448704-tert-Butyl-6-morpholin-4-ylmethyl-pyridin-2-ylamine

Product 1

HCID 57863418N-(4-tert-butyl-6-morpholin-4-ylmethyl-pyridin-2-yl)-2-[2-fluoro-4-(7-pyridin-4-yl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-acetamide

Sources & evidence

ORD record
ord-03ec183296bb4de7b307be8cf184cfa1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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