Tetrahydrofuran → 7-Hydroxy-2-phenyl-4-trimethylsilanylethynyl-thiazolo[4,5-c]pyridine-6 carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:22])[c:8]2[c:9]([c:10]([Br:12])[n:11]1)[n:13][c:14](-[c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[s:15]2.[CH3:23][Si:24]([CH3:25])([CH3:26])[C:27]#[CH:28].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cu:41][I:42].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:22])[c:8]2[c:9]([c:10]([C:28]#[C:27][Si:24]([CH3:23])([CH3:25])[CH3:26])[n:11]1)[n:13][c:14](-[c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[s:15]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d8af861ac0094da0a4947dddadaec2e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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