1,2-Dichloroethane → 3-(2,6-difluorophenyl)-N-[2-hydroxy-1-(7-methoxynaphthalen-2-yl)ethyl]prop-2-enamide
Reaction equation
[CH2:30]([Cl:31])[CH2:32][Cl:33].[CH2:35]([N:36]([CH2:37][CH3:38])[CH2:39][CH3:40])[CH3:41].[CH3:42][N:43]([c:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1)[CH3:50].[Cl:51][CH2:52][Cl:53].[ClH:34].[F:17][c:18]1[c:19]([CH:20]=[CH:21][C:22](=[O:23])[OH:24])[c:25]([F:29])[cH:26][cH:27][cH:28]1.[NH2:1][CH:2]([CH2:3][OH:4])[c:5]1[cH:6][c:7]2[cH:8][c:9]([O:15][CH3:16])[cH:10][cH:11][c:12]2[cH:13][cH:14]1>>[NH:1]([CH:2]([CH2:3][OH:4])[c:5]1[cH:6][c:7]2[cH:8][c:9]([O:15][CH3:16])[cH:10][cH:11][c:12]2[cH:13][cH:14]1)[C:22]([CH:21]=[CH:20][c:19]1[c:18]([F:17])[cH:28][cH:27][cH:26][c:25]1[F:29])=[O:23]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3b9057751d6d4110a7712306591a5576
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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