Tetrahydrofuran → tert-Butyl 4-(4-((2-pyridinyl)-methoxy)phenyl)-4-oxobutyrate
Reaction equation
[Br:32][CH2:33][C:34]([O:35][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:36].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:22][Si:23]([N-:24][Si:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30].[CH3:46][N:47]1[CH2:48][CH2:49][CH2:50][N:51]([CH3:52])[C:53]1=[O:54].[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60].[Li+:31].[n:1]1[c:2]([CH2:7][O:8][c:9]2[cH:10][cH:11][c:12]([C:15]([CH2:16][CH2:17][C:18](=[O:19])[OH:20])=[O:21])[cH:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH2:7][O:8][c:9]2[cH:10][cH:11][c:12]([C:15]([CH2:16][CH2:17][C:18](=[O:19])[O:20][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:21])[cH:13][cH:14]2)[cH:3][cH:4][cH:5][cH:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8a2f82c888bd4859a05de79e42ed13e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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