反应详情

A mixture of 40% aqueous methylamine (70 mL) and camphoric anhydride (5 g) was stirred at room temperature for 30 minutes. To this N,N-dimethyl-4-aminopyridine (DMAP) (0.67 g, 5.4 mmol) was added and stirred further for 24 hours. The reaction mixture was allowed to cool to room temperature and acidified with con. HCl at 0-5° C. White precipitate formed was filtered and dried (5.2 g). m/z (M+H): 214.1.

1. stirringstirred further for 24 hours
2. temperatureto cool to room temperature
3. customat 0-5° C
4. customWhite precipitate
5. customformed
6. filtrationwas filtered
7. customdried (5.2 g)