Potassium Cation → 4-Chloro-1-(4-methylbenzene-1-sulfonyl)-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine

HRID 134058Notes

Reaction equation

HRID 134058 reaction equation
[CH3:30][Si:31]([C:32]([F:33])([F:34])[F:35])([CH3:36])[CH3:37].[CH3:3][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8]1.[CH3:40][O:41][C:42]([CH3:43])([CH3:44])[CH3:45].[Cl:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[n:16]([S:20](=[O:21])(=[O:22])[c:23]1[cH:24][cH:25][c:26]([CH3:29])[cH:27][cH:28]1)[cH:17][c:18]2[I:19].[Cu:38][I:39].[F-:1].[K+:2].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[Cl:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[n:16]([S:20](=[O:21])(=[O:22])[c:23]1[cH:24][cH:25][c:26]([CH3:29])[cH:27][cH:28]1)[cH:17][c:18]2[C:32]([F:33])([F:34])[F:35]

Participants

9

Reactant 8

HCID 813Potassium CationHCID 6228DimethylformamideHCID 84541-MethylpyrrolidineHCID 15413tert-Butyl methyl etherHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 552549(Trifluoromethyl)trimethylsilaneHCID 534382524-Chloro-3-iodo-1-(4-methylbenzene-1-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 116893174-Chloro-1-(4-methylbenzene-1-sulfonyl)-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-c55599101a264ed8954fe1edbe40ab97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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