Hydrochloric Acid → tert-butyl N-methyl-N-[1-[methyl-[1-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]-3-phenylpropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]carbamate

HRID 135691Notes

Reaction equation

HRID 135691 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:12])[OH:13])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1.[CH3:36][N:37]([CH3:38])[CH2:39][CH2:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH3:46].[CH3:47][c:48]1[n:49][o:50][c:51]([CH2:53][O:54][CH2:55][CH:56]([CH2:57][c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[NH:64][CH3:65])[n:52]1.[CH3:69][N:70]([CH3:71])[CH:72]=[O:73].[CH3:74][CH2:75][O:76][C:77](=[O:78])[CH3:79].[Cl:66][CH2:67][Cl:68].[ClH:35].[OH:25][n:26]1[c:27]2[n:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[CH:10]([C:11](=[O:12])[N:64]([CH:56]([CH2:55][O:54][CH2:53][c:51]1[o:50][n:49][c:48]([CH3:47])[n:52]1)[CH2:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH3:65])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 181649HOAtHCID 223269722-[Methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-naphthalen-2-ylpropanoic acidHCID 22327127HCID 22327127, compound

Product 1

HCID 20827580tert-butyl N-methyl-N-[1-[methyl-[1-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]-3-phenylpropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]carbamate

Sources & evidence

ORD record
ord-d1df5473497c408bbc0821d76469f481
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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