1,2-Dichloroethane → N-[1-(4-bromo-2-fluorophenyl)ethyl]-1-[(2,2,2-trifluoroacetyl)amino]cyclopropane-1-carboxamide
Reaction equation
[Br:2][c:3]1[cH:4][c:5]([F:12])[c:6]([CH:9]([CH3:10])[NH3+:11])[cH:7][cH:8]1.[CH2:26]([Cl:27])[CH2:28][Cl:29].[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[Cl-:1].[F:13][C:14]([C:15](=[O:16])[NH:17][C:18]1([C:21](=[O:22])[OH:23])[CH2:19][CH2:20]1)([F:24])[F:25].[OH2:42]>>[Br:2][c:3]1[cH:4][c:5]([F:12])[c:6]([CH:9]([CH3:10])[NH:11][C:21]([C:18]2([NH:17][C:15]([C:14]([F:13])([F:24])[F:25])=[O:16])[CH2:19][CH2:20]2)=[O:22])[cH:7][cH:8]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3e73968d78cc45dd9e3a7f528851ed4f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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