Dimethylformamide → HCID 86624929, compound

HRID 136872Notes

Reaction equation

HRID 136872 reaction equation
[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cu:47][I:48].[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[c:12]2[cH:13][cH:14][cH:15][c:16]3[cH:17][c:18]([C:22]#[CH:23])[cH:19][cH:20][c:21]23)[cH:6][cH:7][cH:8]1)([F:24])[F:25].[NH2:26][c:27]1[n:28][c:29]([Cl:34])[cH:30][c:31]([Cl:33])[n:32]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[Pd:49]([Cl:50])[Cl:51].[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1.[c:71]1([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[cH:85][cH:86][cH:87][cH:88][cH:89]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[c:12]2[cH:13][cH:14][cH:15][c:16]3[cH:17][c:18]([C:22]#[C:23][c:31]4[cH:30][c:29]([Cl:34])[n:28][c:27]([NH2:26])[n:32]4)[cH:19][cH:20][c:21]23)[cH:6][cH:7][cH:8]1)([F:24])[F:25]

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 655222-Amino-4,6-dichloropyrimidineHCID 86624930HCID 86624930, compound

Product 1

HCID 86624929HCID 86624929, compound

Sources & evidence

ORD record
ord-c0fe05c390484584a9b2c917db9f0278
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…