HRID1388095

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID992

Pentachlorophenol

C6HCl5O

HCID6378

(+/-)-1,2-Propylene oxide

C3H6O

HCID7540

Triphenyl phosphite

C18H15O3P

结构：O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

HCID107526

未命名化合物

HCID5359268

Aluminum

PRODUCTS

生成物

结构：CC1CO1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.c1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1

HCID86733446

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23925

Iron

溶剂HCID8471

Triethylamine

C6H15N

CONDITIONS

反应条件

温度: 140 °C

PROCEDURE

实验过程

A 1-liter flask, standardly equipped, was charged with 90 grams of dextrose and 85.2 grams of triphenylphosphite and heated to 140° C. 266 grams of pentachlorophenol containing about 750 ppm aluminum and iron compounds was added. Then propylene oxide was added dropwise with stirring at up to 150° C. After cooling, 4.5 grams of triethylamine was added and oxypropylation continued until the acid number was 0.3. The mixture was then stripped for 3 hours at 84°-88° C./1 mm. Hg. The 689 grams of oxypropylated product had the following properties.

WORKUP

后处理

customA 1-liter flask, standardly equipped
temperatureAfter cooling

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e32eb0bff44047d38133910f3c82984b
来源数据集: uspto-grants-1984_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04430247
来源说明: uspto-grants-1984_02

反应 SMILES

[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[C:13]1([O:19][P:20]([O:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Cl:35][C:36]1[C:41]([OH:42])=[C:40]([Cl:43])[C:39]([Cl:44])=[C:38]([Cl:45])[C:37]=1[Cl:46].[Al].[CH2:48]1[O:51][CH:49]1[CH3:50]>[Fe].C(N(CC)CC)C>[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[C:29]1([O:28][P:20]([O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[O:19][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1.[Cl:35][C:36]1[C:41]([OH:42])=[C:40]([Cl:43])[C:39]([Cl:44])=[C:38]([Cl:45])[C:37]=1[Cl:46].[CH2:48]1[O:51][CH:49]1[CH3:50]