2-Methyl-3-butyn-2-ol → 4-(3-hydroxy-3-methylbut-1-yn-1-yl)benzaldehyde

HRID 140469Notes

Reaction equation

HRID 140469 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1.[CH3:10][C:11]([CH3:12])([C:13]#[CH:14])[OH:15].[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cu:35][I:36].[c:16]1([P:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[c:2]1([C:14]#[C:13][C:11]([CH3:10])([CH3:12])[OH:15])[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1

Participants

6

Reactant 5

HCID 82582-Methyl-3-butyn-2-olHCID 8471TriethylamineHCID 11776TriphenylphosphineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 707414-Bromobenzaldehyde

Product 1

HCID 31574624-(3-hydroxy-3-methylbut-1-yn-1-yl)benzaldehyde

Sources & evidence

ORD record
ord-52241834e9e14d25aad0776b90706e1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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