Hydrochloric Acid → 52055-23-9

HRID 1415508Notes

Reaction equation

HRID 1415508 reaction equation
C(OCC)(=O)C.[ClH:7].[CH2:8]([O:15][C:16]1[CH:27]=[C:26]2[C:19]([NH:20][CH:21]=[C:22]2[CH2:23][CH2:24][NH2:25])=[CH:18][CH:17]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>C(O)(C)C>[ClH:7].[CH2:8]([O:15][C:16]1[CH:27]=[C:26]2[C:19]([NH:20][CH:21]=[C:22]2[CH2:23][CH2:24][NH2:25])=[CH:18][CH:17]=1)[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 895762-[5-(Benzyloxy)-1H-indol-3-yl]ethan-1-amine

Product 1

HCID 282878552055-23-9

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

An ethyl acetate solution saturated with hydrochloric acid was added to a solution of 10 g of 5-benzyloxy-tryptamine in 200 ml of isopropanol until the pH was 1-2 and the mixture was vacuum filtered. The crystals were washed with ethyl acetate and dried under reduced pressure to obtain 11.3 g of 5-benzyloxy-tryptamine hydrochloride melting at 250° C.

Workup

  1. filtrationfiltered
  2. washThe crystals were washed with ethyl acetate
  3. customdried under reduced pressure

Sources & evidence

ORD record
ord-1c1a01720dc44e5eb030897af143d39e
Source dataset
uspto-grants-1977_01
Patent number
US04005206

Reaction notes

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