反应详情

A 1.10 g (5.87 mmol) sample of 1-BOC-2-(R)-azetidinemethanol, prepared in step 62b above, and 588 g (5.87 mmol) of 3-hydroxypyridine were reacted with triphenylphosphine and DEAD (7.05 mmol each) in 100 mL of THF according to the procedure of Example 14a, to give the title compound.