HRID1434525

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13831

Tributylphosphine

C12H27P

HCID97268

Di-tert-butyl azodicarboxylate

C10H18N2O4

结构：Cc1cc(NC(=O)[C@H](C)[C@H](CO)NC(=O)OCc2ccccc2)ccc1N1CCOCC1=O

HCID86605956

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(N2C[C@H](NC(=O)OCc3ccccc3)[C@@H](C)C2=O)ccc1N1CCOCC1=O

HCID86605957

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Prepared analogously to Example 2c from benzyl {(1R,2R)-1-hydroxymethyl-2-[3-methyl-4-(3-oxo-morpholin-4-yl)-phenylcarbamoyl]-propyl}-carbamate with di-tert.-butyl azodicarboxylate and tributylphosphine in THF and subsequent purification by reversed-phase chromatography.