Hydrochloric Acid → Tert-butyl 1-{3-[4-(5-oxo-1,2,4-oxadiazolin-3-yl)phenyl]-2-oxo-5-oxazolidinylcarbonyl}piperidine-4carboxylate

HRID 146795Notes

Reaction equation

HRID 146795 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1.[CH3:53][N:54]([CH3:55])[CH2:56][CH2:57][CH2:58][N:59]=[C:60]=[N:61][CH2:62][CH3:63].[ClH:52].[NH:29]1[CH2:30][CH2:31][CH:32]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:33][CH2:34]1.[O:64]=[CH:65][N:66]([CH3:67])[CH3:68].[O:8]=[c:9]1[nH:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([N:20]3[C:21](=[O:28])[O:22][CH:23]([C:25](=[O:26])[OH:27])[CH2:24]3)[cH:18][cH:19]2)[n:12][o:13]1.[OH2:69].[OH:42][n:43]1[c:44]2[cH:45][cH:46][cH:47][cH:48][c:49]2[n:50][n:51]1>>[O:8]=[c:9]1[nH:10][c:11](-[c:14]2[cH:15][cH:16][c:17]([N:20]3[C:21](=[O:28])[O:22][CH:23]([C:25](=[O:27])[N:29]4[CH2:30][CH2:31][CH:32]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:33][CH2:34]4)[CH2:24]3)[cH:18][cH:19]2)[n:12][o:13]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 1512676Tert-butyl Piperidine-4-carboxylateHCID 1360051203-[4-(5-Oxo-1,2,4-oxadiazolin-3-yl)phenyl]-2-oxo-5-oxazolidinecarboxylic acid

Product 1

HCID 136146332Tert-butyl 1-{3-[4-(5-oxo-1,2,4-oxadiazolin-3-yl)phenyl]-2-oxo-5-oxazolidinylcarbonyl}piperidine-4carboxylate

Sources & evidence

ORD record
ord-d54e17237b7e45a687f0a8bb5ba29af9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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