4-Chlorobenzaldehyde → 4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

HRID 1490628Notes

Reaction equation

HRID 1490628 reaction equation
O=Cc1ccc(Cl)cc1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)N.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.C[OH2+].C[OH2+].Nc1cccc2cccnc12.[Ir].[Ir]>CC1(C)OB(c2cc(Cl)ccc2C=O)OC1(C)C

Participants

8

Reactant 1

HCID 77264-Chlorobenzaldehyde

Product 1

HCID 735535174-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehydeYield 78%

Reagents, catalysts & solvents 6

HCID 6385Tert-ButylamineReagentHCID 113598-AminoquinolineReagentHCID 2733548Bis(pinacolato)diboraneReagentHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolaneReagentHCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridiumCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-324546293c7b460ea163a709754bb58d
Source dataset
Borylation dataset from Roche

Reaction notes

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