反应详情

BnBr was added to the mixture of alcohol and NaH in DMF cooled in an ice bath. The mixture was stirred at room temperature overnight and the solid was filtered. The solvent was removed and the residue was purified by column chromatography to give compound 1.

1. temperaturecooled in an ice bath
2. filtrationthe solid was filtered
3. customThe solvent was removed
4. customthe residue was purified by column chromatography