Hydrochloric Acid → 4-(Bromomethyl)-5-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole
Reaction equation
[Br:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:2][c:3]1[n:4][c:5](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:6][c:7]1[CH3:8].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[ClH:1].[N:34]([C:35]([CH3:36])([CH3:37])[C:38]#[N:39])=[N:40][C:41]([CH3:42])([CH3:43])[C:44]#[N:45].[OH2:52]>>[CH2:2]([c:3]1[n:4][c:5](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:6][c:7]1[CH3:8])[Br:26]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-7a796e8336cb4d56a682cdb6a7ef628d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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