Hydrochloric Acid → 6-Fluoro-3-(4-hydroxyphenoxy)-2-pyrazinecarbonitrile

HRID 1536793Notes

Reaction equation

HRID 1536793 reaction equation
[C:19](=[O:20])([O-:21])[O-:22].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[ClH:25].[F:1][c:2]1[c:3]([C:9]#[N:10])[n:4][c:5]([F:8])[cH:6][n:7]1.[K+:23].[K+:24].[OH2:31].[OH:11][c:12]1[cH:13][cH:14][c:15]([OH:16])[cH:17][cH:18]1>>[c:2]1([O:11][c:12]2[cH:13][cH:14][c:15]([OH:16])[cH:17][cH:18]2)[c:3]([C:9]#[N:10])[n:4][c:5]([F:8])[cH:6][n:7]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 785HydroquinoneHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 226628293,6-Difluoropyrazine-2-carbonitrile

Product 1

HCID 226628546-Fluoro-3-(4-hydroxyphenoxy)-2-pyrazinecarbonitrile

Sources & evidence

ORD record
ord-131523f0893b4547801185be19dc2e6e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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