Hydrochloric Acid → 2-Methyl-3-[1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridin-4-yl]-6-(3-methylpiperazin-1-yl)imidazo[1,2-b]pyridazine

HRID 1537935Notes

Reaction equation

HRID 1537935 reaction equation
[CH2:45]([OH:46])[CH2:47][CH2:48][CH2:49][CH3:50].[CH3:31][CH:32]1[NH:33][CH2:34][CH2:35][NH:36][CH2:37]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8](-[c:12]1[c:13]3[c:14]([n:15][cH:16][cH:17]1)[n:18]([S:21](=[O:22])(=[O:23])[c:24]1[cH:25][cH:26][c:27]([CH3:30])[cH:28][cH:29]1)[cH:19][cH:20]3)[c:9]([CH3:11])[n:10]2.[ClH:51]>>[c:2]1([N:36]2[CH2:35][CH2:34][NH:33][CH:32]([CH3:31])[CH2:37]2)[cH:3][cH:4][c:5]2[n:6]([n:7]1)[c:8](-[c:12]1[c:13]3[c:14]([n:15][cH:16][cH:17]1)[n:18]([S:21](=[O:22])(=[O:23])[c:24]1[cH:25][cH:26][c:27]([CH3:30])[cH:28][cH:29]1)[cH:19][cH:20]3)[c:9]([CH3:11])[n:10]2

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 62761-PentanolHCID 8471TriethylamineHCID 660572-MethylpiperazineHCID 580463686-chloro-2-methyl-3-{1-[(4-methylphenyl)sulphonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}imidazo[1,2-b]pyridazine

Product 1

HCID 670165212-Methyl-3-[1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridin-4-yl]-6-(3-methylpiperazin-1-yl)imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-9e28ec688fbf4120b2d469b6bdfdef66
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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