HRID1539939

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID65578

Ethanedioyl dichloride

C2Cl2O2

HCID81531

Diisopropylethylamine

C8H19N

HCID84432

4-Amino-2-chloropyridine

C5H5ClN2

HCID59313818

未命名化合物

HCID59313908

未命名化合物

结构：O=C(Nc1ccnc(Cl)c1)c1cnc2c(Cl)cc(Cl)nn12

HCID59624781

6,8-Dichloro-N-(2-chloropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

C12H6Cl3N5O

PRODUCTS

生成物

结构：O=C(Nc1ccnc(Cl)c1)c1cnc2c(Br)cc(Cl)nn12

HCID59624531

8-Bromo-6-chloro-N-(2-chloropyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

C12H6BrCl2N5O

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4362ce483de342b0b2a2eb951c083f4e
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应 SMILES

[Br:15][c:16]1[c:17]2[n:18]([n:19][c:20]([Cl:22])[cH:21]1)[c:23]([C:26](=[O:27])[OH:28])[cH:24][n:25]2.[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[CH:48]([N:49]([CH2:50][CH3:51])[CH:52]([CH3:53])[CH3:54])([CH3:55])[CH3:56].[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[c:6]2[n:7]([c:8]([C:9]([OH:10])=[O:11])[cH:12][n:13]2)[n:14]1.[Cl:29][C:30]([C:31]([Cl:32])=[O:33])=[O:34].[Cl:40][c:41]1[n:42][cH:43][cH:44][c:45]([NH2:47])[cH:46]1.[Cl:57][c:58]1[cH:59][c:60]([Cl:61])[c:62]2[n:63]([c:64]([C:65]([NH:66][c:67]3[cH:68][cH:69][n:70][c:71]([Cl:72])[cH:73]3)=[O:74])[cH:75][n:76]2)[n:77]1>>[Br:15][c:16]1[c:17]2[n:18]([n:19][c:20]([Cl:22])[cH:21]1)[c:23]([C:26](=[O:28])[NH:47][c:45]1[cH:44][cH:43][n:42][c:41]([Cl:40])[cH:46]1)[cH:24][n:25]2