Tetrahydrofuran → 1-(2-propynyl)-3-trifluoromethyl-1H-pyrrole-4-methanol
Reaction equation
[Al+3:2].[CH2:7]([C:8]#[CH:9])[n:10]1[cH:11][c:12]([C:20]([F:21])([F:22])[F:23])[c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:14]1.[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[H-:1].[H-:24].[H-:4].[H-:5].[H-:6].[K:25].[Li+:3].[Na:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[CH2:7]([C:8]#[CH:9])[n:10]1[cH:11][c:12]([C:20]([F:21])([F:22])[F:23])[c:13]([CH2:15][OH:16])[cH:14]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-53a944aee8344535938ed1f93030de48
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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