Acetate → Tert-butyl 2-(4-fluoroanilino)-4-[2-(2-methoxyphenyl)ethenyl]benzoate

HRID 1553159Notes

Reaction equation

HRID 1553159 reaction equation
[B-:46]([F:47])([F:48])([F:49])[F:50].[C:51]([P:52]([C:53]([CH3:54])([CH3:55])[CH3:56])[C:57]([CH3:58])([CH3:59])[CH3:60])([CH3:61])([CH3:62])[CH3:63].[C:77]([O-:78])(=[O:79])[CH3:80].[C:82]([O-:83])(=[O:84])[CH3:85].[CH3:33][CH2:34][CH2:35][CH2:36][N:37]([CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH2:44][CH3:45].[CH3:86][CH2:87][O:88][C:89](=[O:90])[CH3:91].[CH3:92][N:93]([CH3:94])[C:95](=[O:96])[CH3:97].[F:1][c:2]1[cH:3][cH:4][c:5]([NH:6][c:7]2[c:8]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[cH:16][cH:17][c:18]([CH:20]=[CH2:21])[cH:19]2)[cH:22][cH:23]1.[I:24][c:25]1[c:26]([O:31][CH3:32])[cH:27][cH:28][cH:29][cH:30]1.[OH:64][C:65]([CH2:66][C:67]([C:68](=[O:69])[OH:70])([CH2:71][C:72](=[O:73])[OH:74])[OH:75])=[O:76].[Pd+2:81]>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:6][c:7]2[c:8]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[cH:16][cH:17][c:18]([CH:20]=[CH:21][c:25]3[c:26]([O:31][CH3:32])[cH:27][cH:28][cH:29][cH:30]3)[cH:19]2)[cH:22][cH:23]1

Participants

11

Reactant 10

HCID 175Acetate2×HCID 311Citric AcidHCID 7622TributylamineHCID 8857Ethyl AcetateHCID 26255TetrafluoroborateHCID 31374DimethylacetamideHCID 68257o-IodoanisoleHCID 83681Tris(1,1-dimethylethyl)phosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 68959213Tert-butyl 2-(4-fluoroanilino)-4-vinylbenzoate

Product 1

HCID 68966081Tert-butyl 2-(4-fluoroanilino)-4-[2-(2-methoxyphenyl)ethenyl]benzoate

Sources & evidence

ORD record
ord-a796f045fdad4ffebab5b56c5e39a7b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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