Dimethylformamide → HCID 10309452, compound

HRID 1553927Notes

Reaction equation

HRID 1553927 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH3:22])[cH:7][c:8]([C:11](=[O:12])[NH:13][CH2:14][c:15]3[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[c:9]2=[O:10])[o:23]1.[CH2:24]([CH2:25][C:26]#[CH:27])[OH:28].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cu:41][I:42].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[Pd:43]([Cl:44])[Cl:45].[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1.[c:65]1([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[cH:79][cH:80][cH:81][cH:82][cH:83]1>>[c:2]1([C:27]#[C:26][CH2:25][CH2:24][OH:28])[cH:3][c:4]2[c:5]([n:6]([CH3:22])[cH:7][c:8]([C:11](=[O:12])[NH:13][CH2:14][c:15]3[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]3)[c:9]2=[O:10])[o:23]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 135663-Butyn-1-OLHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 10237594HCID 10237594, compound

Product 1

HCID 10309452HCID 10309452, compound

Sources & evidence

ORD record
ord-80e2a4e05eed411e8802c257c7086279
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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