1,2-Dichloroethane → 2-Chloro-N-methoxy-N-methylisonicotinamide

HRID 1556126Notes

Reaction equation

HRID 1556126 reaction equation
[CH2:17]([Cl:18])[CH2:19][Cl:20].[CH3:13][NH:14][O:15][CH3:16].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH3:8])[cH:9][cH:10][n:11]1.[ClH:12].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42].[OH2:43].[OH:21][n:22]1[c:23]2[c:24]([cH:25][cH:26][cH:27][cH:28]2)[n:29][n:30]1>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:7]([CH3:8])[O:15][CH3:16])[cH:9][cH:10][n:11]1

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 14232N,O-DimethylhydroxylamineHCID 757711-HydroxybenzotriazoleHCID 151158492-chloro-N-methylisonicotinamide

Product 1

HCID 185068942-Chloro-N-methoxy-N-methylisonicotinamide

Sources & evidence

ORD record
ord-37043c33079a4eb9bb99e7004553468c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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