Water → 1-[3-(4-(4-Hydroxyphenyl)-1-piperazinyl)propyl]-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

HRID 1562288Notes

Reaction equation

HRID 1562288 reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[Cl:1][CH2:2][CH2:3][CH2:4][N:5]1[S:6](=[O:17])(=[O:18])[N:7]2[CH2:8][CH2:9][CH2:10][c:11]3[cH:12][cH:13][cH:14][c:15]1[c:16]32.[OH2:39].[OH:19][c:20]1[cH:21][cH:22][c:23]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:24][cH:25]1>>[CH2:2]([CH2:3][CH2:4][N:5]1[S:6](=[O:17])(=[O:18])[N:7]2[CH2:8][CH2:9][CH2:10][c:11]3[cH:12][cH:13][cH:14][c:15]1[c:16]32)[N:29]1[CH2:28][CH2:27][N:26]([c:23]2[cH:22][cH:21][c:20]([OH:19])[cH:25][cH:24]2)[CH2:31][CH2:30]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 92467p-(1-Piperazinyl)phenolHCID 198884501-(3-chloropropyl)-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

Product 1

HCID 198884561-[3-(4-(4-Hydroxyphenyl)-1-piperazinyl)propyl]-5,6-dihydro(1H,4H)-1,2,5-thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide

Sources & evidence

ORD record
ord-7fcb80414d094f1d9ef24aa722a168e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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