Chloride → 1-[5-(1,2-Bis{[tert-butyl(dimethyl)silyl]oxy}ethyl)pyridin-2-yl]-6-cyclopentyl-5-[5-(methylsulfanyl)pyridin-2-yl]hexane-1,4-dione

HRID 1563843Notes

Reaction equation

HRID 1563843 reaction equation
[C:28]([CH3:29])([CH3:30])([CH3:31])[Si:32]([O:33][CH:34]([CH2:35][O:36][Si:37]([CH3:38])([CH3:39])[C:40]([CH3:41])([CH3:42])[CH3:43])[c:44]1[cH:45][cH:46][c:47]([CH:50]=[O:51])[n:48][cH:49]1)([CH3:52])[CH3:53].[CH2:55]([n+:56]1[c:57]([CH3:58])[c:59]([CH2:60][CH2:61][OH:62])[s:63][cH:64]1)[c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1.[CH3:20][CH2:21][OH:22].[CH3:71][CH2:72][O:73][C:74](=[O:75])[CH3:76].[CH3:77][CH2:78][N:79]([CH2:80][CH3:81])[CH2:82][CH3:83].[CH:1]1([CH2:6][CH:7]([C:8]([CH:9]=[CH2:10])=[O:11])[c:12]2[n:13][cH:14][c:15]([S:18][CH3:19])[cH:16][cH:17]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl-:54].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[CH:1]1([CH2:6][CH:7]([C:8]([CH2:9][CH2:10][C:50]([c:47]2[cH:46][cH:45][c:44]([CH:34]([O:33][Si:32]([C:28]([CH3:29])([CH3:30])[CH3:31])([CH3:52])[CH3:53])[CH2:35][O:36][Si:37]([CH3:38])([CH3:39])[C:40]([CH3:41])([CH3:42])[CH3:43])[cH:49][n:48]2)=[O:51])=[O:11])[c:12]2[n:13][cH:14][c:15]([S:18][CH3:19])[cH:16][cH:17]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

9

Reactant 8

HCID 312ChlorideHCID 702EthanolHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 4253053-Benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-iumHCID 593315425-Cyclopentyl-4-[5-(methylsulfanyl)pyridin-2-yl]pent-1-en-3-oneHCID 593316215-(1,2-Bis{[tert-butyl(dimethyl)silyl]oxy}ethyl)pyridine-2-carbaldehyde

Product 1

HCID 593314141-[5-(1,2-Bis{[tert-butyl(dimethyl)silyl]oxy}ethyl)pyridin-2-yl]-6-cyclopentyl-5-[5-(methylsulfanyl)pyridin-2-yl]hexane-1,4-dione

Sources & evidence

ORD record
ord-0abed1ab49414cab8dff4cb070f173e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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