Methanol → HCID 54577314, compound

HRID 1565078Notes

Reaction equation

HRID 1565078 reaction equation
[CH3:40][N:41]([c:42]1[cH:43][cH:44][n:45][cH:46][cH:47]1)[CH3:48].[CH3:57][OH:58].[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:12][c:13]1[c:14](-[c:24]2[n:25][cH:26][c:27]([NH2:30])[n:28][cH:29]2)[cH:15][c:16]2[c:17]([cH:23]1)[O:18][C:19]([F:21])([F:22])[O:20]2.[Cl:49][CH2:50][Cl:51].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([F:11])[cH:8][cH:9][cH:10]1.[Li+:59].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1.[OH-:60]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:30][c:27]2[cH:26][n:25][c:24](-[c:14]3[c:13]([Cl:12])[cH:23][c:17]4[c:16]([cH:15]3)[O:20][C:19]([F:21])([F:22])[O:18]4)[cH:29][n:28]2)[c:7]([F:11])[cH:8][cH:9][cH:10]1

Participants

10

Reactant 9

HCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 142844-(Dimethylamino)pyridineHCID 28486Lithium ionHCID 81531DiisopropylethylamineHCID 874382,6-Difluorobenzoyl chlorideHCID 58486825HCID 58486825, compound

Product 1

HCID 54577314HCID 54577314, compound

Sources & evidence

ORD record
ord-b341496c673543fba5b53b2bd5f82579
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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