Hexane → 3-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridine

HRID 1567672Notes

Reaction equation

HRID 1567672 reaction equation
[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[CH3:23][Si:24]([CH3:25])([CH3:26])[C:27]#[CH:28].[CH3:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34].[CH3:35][O:36][CH2:37][CH2:38][O:39][CH3:40].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cu:41][I:42].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[cH:8][n:9][cH:10][c:11]([Cl:13])[cH:12]1)(=[O:14])=[O:15]>>[c:7]1([C:28]#[C:27][Si:24]([CH3:23])([CH3:25])[CH3:26])[cH:8][n:9][cH:10][c:11]([Cl:13])[cH:12]1

Participants

8

Reactant 7

HCID 8058HexaneHCID 80711,2-DimethoxyethaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 151858705-Chloropyridin-3-yl trifluoromethanesulfonate

Product 1

HCID 235008913-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridine

Sources & evidence

ORD record
ord-42bca4e98530455baa8d6621529cf387
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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