Bromide ion → (3,5-Difluoro-4-hydroxy-phenyl)-(2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone
Reaction equation
[Br-:24].[CH2:25]1[NH:26][CH2:27][CH2:28][NH:29][CH2:30]1.[CH:33]([N:34]([CH3:35])[CH3:36])=[O:37].[ClH:31].[F:1][c:2]1[cH:3][c:4]([C:11](=[O:12])[N:13]2[c:14]3[c:15]([cH:19][cH:20][n:21][cH:22]3)[O:16][CH2:17][CH2:18]2)[cH:5][c:6]([F:10])[c:7]1[O:8][CH3:9].[Li+:23].[OH2:32]>>[F:1][c:2]1[cH:3][c:4]([C:11](=[O:12])[N:13]2[c:14]3[c:15]([cH:19][cH:20][n:21][cH:22]3)[O:16][CH2:17][CH2:18]2)[cH:5][c:6]([F:10])[c:7]1[OH:8]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2e461440cfbf4e7ea65c98fb28950e8b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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